SCHEMBL31723231

SCHEMBL31723231

Cc1cc(N)c(Cl)c(Nc2cccc(F)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.53
DEPTOR Q8TB45 1/20 0.41
EGFR P00533 2/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
ABL1 P00519 1/20 0.39
ABL2 P42684 1/20 0.39
KDR P35968 1/20 0.38
TAAR1 Q96RJ0 2/20 0.38
ACHE P22303 1/20 0.38
P2RY4 P51582 2/20 0.38
ABCG2 Q9UNQ0 2/20 0.37
MEN1 O00255 2/20 0.37
RAB9A P51151 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22231784 1.00 RAPGEF4 (0.53) RAPGEF4DEPTOREGFRPTGS1PTGS2
SCHEMBL29454093 1.00 RAPGEF4 (0.53) RAPGEF4DEPTOREGFRPTGS1PTGS2
SCHEMBL29454112 0.86 NPSR1 (0.49) RAPGEF4EGFRP2RY4RAB9ANPC1
SCHEMBL22231908 0.85 FADS1 (0.46) RAPGEF4EGFRPTGS1PTGS2ABL1
SCHEMBL31723203 0.85 FADS1 (0.46) RAPGEF4EGFRPTGS1PTGS2ABL1
SCHEMBL29454046 0.85 FADS1 (0.46) RAPGEF4EGFRPTGS1PTGS2ABL1
SCHEMBL29454124 0.84 RAPGEF4 (0.47) RAPGEF4EGFRKDM4EHSD17B10L3MBTL1
SCHEMBL31723242 0.84 RAPGEF4 (0.47) RAPGEF4EGFRKDM4EHSD17B10L3MBTL1
SCHEMBL22231721 0.83 BPTF (0.41) RAPGEF4EGFRMEN1RAB9AKMT2A
SCHEMBL29454349 0.83 BPTF (0.41) RAPGEF4EGFRMEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed