SCHEMBL29454339

SCHEMBL29454339

Cc1c(N)cc(F)cc1Nc1ccccc1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNC P24863 1/20 0.40
CDK8 P49336 1/20 0.40
MAPK10 P53779 1/20 0.38
CXCL8 P10145 1/20 0.37
MAPT P10636 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 2/20 0.37
HPGD P15428 2/20 0.37
USP2 O75604 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 1/20 0.37
LRRK2 Q5S007 1/20 0.37
PTK2 Q05397 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454099 1.00 CCNC (0.40) CCNCCDK8MAPK10CXCL8MAPT
SCHEMBL22232266 1.00 CCNC (0.40) CCNCCDK8MAPK10CXCL8MAPT
SCHEMBL29454081 0.87 SLC6A4 (0.39) CCNCCDK8MAPK10CXCL8MAPT
SCHEMBL22232279 0.87 MAPK13 (0.43) MAPK10RAB9ASMN1; SMN2ALDH1A1NPC1
SCHEMBL22232361 0.84 POLB (0.39) CCNCCDK8MAPK10CXCL8MAPT
SCHEMBL31723263 0.84 POLB (0.39) CCNCCDK8MAPK10CXCL8MAPT
SCHEMBL29454238 0.84 POLB (0.39) CCNCCDK8MAPK10CXCL8MAPT
SCHEMBL29454259 0.83 ALDH1A1 (0.42) MAPTRAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL22232539 0.81 MAPT (0.48) MAPTRAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL31723268 0.81 NUDT1 (0.38) MAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS CCNC 1664/4885CDK8 3239/4885MAPK10 4432/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS CCNC 406/4885CDK8 2902/4885MAPK10 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.