Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 5/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.34 |
| ▸ | GSK3A | P49840 | 5/20 | 0.34 |
| ▸ | GSK3B | P49841 | 5/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723355 | 0.85 | BRAF (0.36) | TNFBRAFCDK1CCNB1GSK3A | |
| SCHEMBL31723352 | 0.85 | BRAF (0.38) | TNFBRAFCDK1CCNB1GSK3A | |
| SCHEMBL30987296 | 0.80 | HSD17B13 (0.41) | HSD17B13TRPA1 | |
| SCHEMBL24879123 | 0.80 | BRAF (0.46) | TNFBRAFHSD17B13LMNA | |
| SCHEMBL31723380 | 0.78 | GRM2 (0.33) | — | |
| SCHEMBL31723379 | 0.75 | MCL1 (0.56) | TNFMCL1DDR1LMNA | |
| SCHEMBL24879033 | 0.74 | CLK1 (0.48) | TNFBRAFHSD17B13LMNA | |
| SCHEMBL31723386 | 0.74 | CDK1 (0.32) | BRAFCDK1CCNB1GSK3AGSK3B | |
| SCHEMBL31723372 | 0.74 | PTPN11 (0.34) | TNF | |
| SCHEMBL29969954 | 0.73 | BRAF (0.42) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |