SCHEMBL31723494

SCHEMBL31723494

COCCO[C@@H]1[C@H](O)[C@@H](CO[Si](C)(C)C(C)(C)C)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 2/20 0.50
P2RY2 P41231 1/20 0.48
P2RY1 P47900 1/20 0.48
P2RY6 Q15077 1/20 0.48
PRMT6 Q96LA8 1/20 0.47
DNPH1 O43598 2/20 0.47
BMPR1B O00238 1/20 0.45
ADORA1 P30542 2/20 0.45
P2RX3 P56373 1/20 0.44
P2RX4 Q99571 1/20 0.44
P2RX2 Q9UBL9 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
NT5E P21589 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26107563 0.92 P2RY12 (0.52) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL7064875 0.88 ADORA1 (0.56) ADORA1ADORA3
SCHEMBL38653713 0.88 ADORA1 (0.56) ADORA1ADORA3
SCHEMBL25966151 0.88 PRMT6 (0.51) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL7064871 0.88 ADORA1 (0.56) ADORA1ADORA3
SCHEMBL16940281 0.88 PRMT6 (0.51) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL19407591 0.88 ADORA1 (0.56) ADORA1ADORA3
SCHEMBL19399423 0.88 PRMT6 (0.51) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL30504222 0.88 P2RY12 (0.53) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL20773178 0.88 P2RY12 (0.53) P2RY12P2RY2P2RY1P2RY6PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346624-A1 POLYNUCLEOTIDE AND PRODUCING METHOD THEREOF EISAI R&D MAN CO LTD (JP) 2025-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346624-A1 POLYNUCLEOTIDE AND PRODUCING METHOD THEREOF POLRMT, POLN, POLM P2RY12 2972/4885P2RY2 3000/4885P2RY1 2821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.