SCHEMBL31723500

SCHEMBL31723500

COCCO[C@@H]1[C@@H](OP(O)N(C(C)C)C(C)(C)CCC#N)[C@@H](COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O[C@H]1n1cc(C)c(=O)[nH]c1=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.36
TK2 O00142 9/20 0.33
TK1 P04183 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34460009 0.89 TYMP (0.33) TYMP
SCHEMBL34460008 0.87 TYMP (0.33) TYMP
SCHEMBL31570211 0.86 TYMP (0.36) TYMPTK2TK1
SCHEMBL31723473 0.84 RNASE1 (0.40) TK2TK1
SCHEMBL7261209 0.84 TYMP (0.36) TYMPTK2TK1
SCHEMBL29530844 0.83 TYMP (0.35) TYMPTK2TK1
SCHEMBL2113954 0.81 TYMP (0.36) TYMPTK2TK1
SCHEMBL327187 0.80 TK2 (0.35) TYMPTK2TK1
SCHEMBL313048 0.79 TYMP (0.44) TYMPTK2TK1
SCHEMBL30216573 0.79 TYMP (0.47) TYMPTK2TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346624-A1 POLYNUCLEOTIDE AND PRODUCING METHOD THEREOF EISAI R&D MAN CO LTD (JP) 2025-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346624-A1 POLYNUCLEOTIDE AND PRODUCING METHOD THEREOF POLRMT, POLN, POLM TYMP 19/4885TK2 107/4885TK1 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.