SCHEMBL31723990

SCHEMBL31723990

NC(=O)C(C(N)=O)N1C(=O)C=CC1=O

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
MGLL Q99685 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
DDAH1 O94760 1/20 0.30
NSD2 O96028 1/20 0.30
G6PD P11413 1/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2347972 0.76 KMT2A (0.49) GSK3AGSK3BMGLLALDH1A1LMNA
SCHEMBL6567846 0.76 LMNA (0.47) GSK3AGSK3BMGLLALDH1A1LMNA
SCHEMBL18932372 0.73 ALDH1A1 (0.38) ALDH1A1LMNAPOLBL3MBTL1
SCHEMBL31723973 0.72 ALDH1A1 (0.37) ALDH1A1LMNAPOLBL3MBTL1
SCHEMBL31031923 0.70 ALDH1A1 (0.36) ALDH1A1LMNAPOLBL3MBTL1
SCHEMBL31723977 0.70 LMNA (0.37) ALDH1A1LMNAMEN1KMT2A
SCHEMBL21507374 0.69 MEN1 (0.33) GSK3AGSK3BMGLLALDH1A1LMNA
SCHEMBL31723989 0.69 ALDH1A1 (0.57) ALDH1A1LMNAHPGDHTTPOLB
SCHEMBL28459680 0.68 DNMT1 (0.34) GSK3AGSK3BMGLLLMNAMEN1
SCHEMBL31723987 0.68 KMT2A (0.36) ALDH1A1LMNAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345488-A1 CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 US disclosed