Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18260473 | 1.00 | ATM (0.49) | ATMCTSSCTSKALDH1A1MTNR1A | |
| SCHEMBL19665873 | 1.00 | ATM (0.49) | ATMCTSSCTSKALDH1A1MTNR1A | |
| SCHEMBL30771269 | 1.00 | ATM (0.49) | ATMCTSSCTSKALDH1A1MTNR1A | |
| SCHEMBL30771314 | 1.00 | ATM (0.49) | ATMCTSSCTSKALDH1A1MTNR1A | |
| SCHEMBL6479034 | 0.88 | ATM (0.54) | ATMALDH1A1MTNR1AMTNR1BPOLB | |
| SCHEMBL6479030 | 0.88 | ATM (0.54) | ATMALDH1A1MTNR1AMTNR1BPOLB | |
| SCHEMBL6121239 | 0.88 | ATM (0.54) | ATMALDH1A1MTNR1AMTNR1BPOLB | |
| SCHEMBL28709127 | 0.87 | CTSK (0.47) | ATMCTSSCTSKGABRB1GABRB2 | |
| SCHEMBL5552871 | 0.87 | FFAR1 (0.48) | ATMCTSSCTSKCACNA1B | |
| SCHEMBL3814656 | 0.86 | ATM (0.44) | ATMCTSSCTSKALDH1A1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | ROCK1, ROCK2, RHOA | ATM 1532/4885CTSS 2671/4885CTSK 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.