Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 18/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31724074 | 0.85 | ROCK2 (0.37) | ROCK2ROCK1 | |
| SCHEMBL31389085 | 0.85 | ROCK2 (0.37) | ROCK2ROCK1 | |
| SCHEMBL30771379 | 0.83 | ROCK1 (0.58) | ROCK2ROCK1 | |
| SCHEMBL31724500 | 0.79 | ACACB (0.46) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL31724389 | 0.79 | ACACB (0.46) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL31724181 | 0.79 | ACACB (0.45) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL31724225 | 0.79 | ACACB (0.45) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL30771333 | 0.73 | ROCK1 (0.59) | ROCK2ROCK1 | |
| SCHEMBL30771354 | 0.73 | ROCK1 (0.59) | ROCK2ROCK1 | |
| SCHEMBL30771367 | 0.73 | ROCK1 (0.59) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | ROCK1, ROCK2, RHOA | ROCK2 2/4885ROCK1 1/4885ACACB 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.