Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31724074 | 1.00 | ROCK2 (0.37) | ROCK2ROCK1SYKCTSSCTSK | |
| SCHEMBL31724366 | 0.85 | ROCK2 (0.49) | ROCK2ROCK1 | |
| SCHEMBL31389107 | 0.76 | CTSS (0.39) | SYKCTSSCTSKMEN1KMT2A | |
| SCHEMBL31724494 | 0.76 | CTSS (0.39) | SYKCTSSCTSKMEN1KMT2A | |
| SCHEMBL31724369 | 0.76 | CTSS (0.39) | SYKCTSSCTSKMEN1KMT2A | |
| SCHEMBL31389093 | 0.76 | CTSS (0.39) | SYKCTSSCTSKMEN1KMT2A | |
| SCHEMBL31724500 | 0.72 | ACACB (0.46) | ROCK2ROCK1 | |
| SCHEMBL31724389 | 0.72 | ACACB (0.46) | ROCK2ROCK1 | |
| SCHEMBL31724225 | 0.72 | ACACB (0.45) | ROCK2ROCK1 | |
| SCHEMBL10380082 | 0.72 | SYK (0.43) | SYKCTSSCTSKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119173509-A | ROCK inhibitors and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-12-20 | — | — | CN | disclosed |