Adamantane

Adamantane

SCHEMBL317246

C.C1C2CC3CC1CC(C2)C3.N

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.40
SLC22A2 O15244 1/20 0.31
SLC22A1 O15245 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
STAT6 P42226 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
SLC47A1 Q96FL8 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adamantane SCHEMBL28003802 0.94 CYP2C9 (0.38) CYP2C9LMNA
Adamantane SCHEMBL7154373 0.94 CYP2C9 (0.38) CYP2C9LMNA
Adamantane SCHEMBL8848421 0.94 CYP2C9 (0.43) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B
Adamantane SCHEMBL870112 0.94 CYP2C9 (0.43) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B
Adamantane SCHEMBL913610 0.94 CYP2C9 (0.43) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B
Adamantane SCHEMBL28551331 0.88 CYP2C9 (0.40) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B
Adamantane SCHEMBL28330886 0.88 CYP2C9 (0.40) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B
Adamantane SCHEMBL21433651 0.88 CYP2C9 (0.40) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B
Adamantane SCHEMBL18065809 0.88 CYP2C9 (0.40) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B
Adamantane SCHEMBL28232364 0.88 CYP2C9 (0.40) CYP2C9SLC22A2SLC22A1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011687-A High-toughness epoxy resin-based carbon fiber prepreg and preparation method thereof 江苏美伦新材料科技有限公司 2026-05-12 CN claimed
CN-116217484-B Naphthalimide derivative based on methylene adamantane modification as well as preparation method and application thereof 苏州大学 2024-04-05 CN claimed
CN-116395671-A Preparation method of magnetic carbon quantum dot with high relaxation rate 中国科学院上海微系统与信息技术研究所 2023-07-07 CN claimed
CN-116285974-A Preparation method of carbon-based quantum dot with high quantum yield and light stability 中国科学院上海微系统与信息技术研究所 2023-06-23 CN claimed
CN-116217484-A Naphthalimide derivative based on methylene adamantane modification as well as preparation method and application thereof 苏州大学 2023-06-06 CN claimed
CN-106478849-A Catalytic component for vinyl polymerization and ethylene rolymerization catalyst 中国石油化工股份有限公司 2017-03-08 CN claimed
CN-106478850-A Preparation method and ethylene rolymerization catalyst for the catalytic component of vinyl polymerization 中国石油化工股份有限公司 2017-03-08 CN claimed
US-8481016-B2 Method for inhibition of potential-dependent cation channel KAO CORPORATION (JP) 2013-07-09 US claimed
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel KAO CORPORATION (JP) 2013-02-21 US claimed
CN-102258788-B Targeted transmission assembly of adriamycin anticancer medicine and preparation method thereof UNIV NANKAI 2012-11-07 CN claimed
CN-102258788-A Targeted transmission assembly of adriamycin anticancer medicine and preparation method thereof 2011-11-30 CN claimed
CN-1665801-B Anti tubercular drug: compositions and methods DEPT OF HEALTH AND HUMAN SERVI 2011-05-11 CN claimed
CN-122011687-A High-toughness epoxy resin-based carbon fiber prepreg and preparation method thereof 江苏美伦新材料科技有限公司 2026-05-12 CN disclosed
EP-4714935-A1 AROMATIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPARATUS Hodogaya Chemical Co., Ltd. (JP) 2026-03-25 EP disclosed
US-12582641-B2 Sulfur-containing compound based on glutarimide skeleton and application thereof SHANGHAITECH UNIVERSITY (CN) 2026-03-24 US disclosed
CN-116874408-B Adamantane-modified fullerene (C) with enhanced fluorescence properties60) Pyrrolidine, microcrystal thereof and preparation method thereof 山东大学 2026-03-20 CN disclosed
CN-1284057-A Adamantane derivatives ASTRA ZENECA BRITISH LTD (GB) 2001-02-14 CN disclosed
CN-1202888-A Isoquinoline derivatives and isoquinoline combinatorial libraries TORREY PINES INST (US) 1998-12-23 CN disclosed
CN-1155546-A Aminomethyl-2,3,8,9-tetrahydro-7H-1,4-dioxino[2,3-e]-indol-8-ones and derivatives AMERICAN HOME PROD (US) 1997-07-30 CN disclosed
EP-0240631-A1 Alkylation of amines and amides ETHYL CORPORATION (US) 1987-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel TRPM7, TRPM8, OR10J3 CYP2C9 795/4885SLC22A2 1777/4885SLC22A1 1732/4885
US-12582641-B2 Sulfur-containing compound based on glutarimide skeleton and application thereof SUCNR1, SRD5A1, GLS CYP2C9 2079/4885SLC22A2 1299/4885SLC22A1 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.