SCHEMBL31725289

SCHEMBL31725289

CC(=O)O[C@@H]1[C@H](F)[C@@H](COC(=O)c2ccc(C)cc2)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PRMT6 Q96LA8 1/20 0.54
▸ LMNA P02545 1/20 0.52
▸ PRKAB2 O43741 1/20 0.51
▸ PRKAG1 P54619 1/20 0.51
▸ PRKAA2 P54646 1/20 0.51
▸ PRKAA1 Q13131 1/20 0.51
▸ PRKAG3 Q9UGI9 1/20 0.51
▸ PRKAG2 Q9UGJ0 1/20 0.51
▸ PRKAB1 Q9Y478 1/20 0.51
▸ P2RY12 Q9H244 3/20 0.44
▸ P2RX3 P56373 1/20 0.43
▸ P2RX4 Q99571 1/20 0.43
▸ P2RX2 Q9UBL9 1/20 0.43
▸ ABCB1 P08183 1/20 0.43
▸ P2RY2 P41231 1/20 0.42
▸ P2RY1 P47900 1/20 0.42
▸ P2RY6 Q15077 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25962308 0.91 PRMT6 (0.56) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL21245357 0.91 LMNA (0.58) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL5982554 0.88 PRMT6 (0.62) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL31725346 0.88 PRMT6 (0.53) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL20149843 0.88 PRMT6 (0.53) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL31725337 0.86 PRMT6 (0.56) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL9850105 0.85 LMNA (0.56) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL13975682 0.85 LMNA (0.56) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL9850107 0.85 LMNA (0.56) PRMT6LMNAPRKAB2PRKAG1PRKAA2
SCHEMBL13170100 0.85 LMNA (0.71) LMNAP2RY12ABCB1P2RY2P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235664-A1 PURINE NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2025-11-13 — — WO disclosed
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