Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 11/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 11/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 11/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 10/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 10/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 10/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 10/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5472147 | 0.83 | KDM4E (0.55) | PRMT5WDR77GSK3AGSK3B | |
| SCHEMBL12502513 | 0.82 | JAK2 (0.46) | PRMT5WDR77GSK3AGSK3BLIPG | |
| SCHEMBL1519972 | 0.79 | PRMT5 (0.42) | PRMT5WDR77GSK3AGSK3BF11 | |
| SCHEMBL30379604 | 0.79 | PRMT5 (0.42) | PRMT5WDR77GSK3AGSK3BF11 | |
| SCHEMBL15799090 | 0.78 | LPL (0.44) | PRMT5WDR77GSK3AGSK3BLIPG | |
| SCHEMBL15799446 | 0.78 | PRMT5 (0.41) | PRMT5WDR77GSK3AGSK3BLIPG | |
| SCHEMBL17588945 | 0.77 | PRMT5 (0.42) | PRMT5WDR77GSK3AGSK3BLIPG | |
| SCHEMBL31725364 | 0.76 | PRMT5 (0.43) | PRMT5WDR77GSK3AGSK3BF2 | |
| SCHEMBL23165855 | 0.76 | YTHDC1 (0.52) | PRMT5WDR77GSK3AGSK3B | |
| SCHEMBL29850421 | 0.76 | YTHDC1 (0.52) | PRMT5WDR77GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235733-A1 | BIS-BICYCLOHETEROARYL MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |