Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.45 |
| ▸ | HTR6 | P50406 | 7/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31725552 | 0.78 | HTR3A (0.46) | HTR3AHTR6ATMHSP90AA1HSP90AB1 | |
| SCHEMBL17176249 | 0.77 | HTR3A (0.60) | HTR3AATM | |
| SCHEMBL19068184 | 0.74 | HTR3A (0.57) | HTR3AATMKMT2A | |
| SCHEMBL27809864 | 0.73 | HSP90AA1 (0.42) | HTR6HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL17170603 | 0.73 | HTR3A (0.59) | HTR3AATM | |
| SCHEMBL1825003 | 0.70 | HTR3A (0.54) | HTR3AATM | |
| SCHEMBL15792325 | 0.69 | DYRK1A (0.49) | DYRK1AGSK3BHSP90AA1HSP90AB1IDO1 | |
| SCHEMBL12146969 | 0.69 | HSP90AA1 (0.42) | HTR6DYRK1AHSP90AA1HSP90AB1IDO1 | |
| SCHEMBL26597000 | 0.69 | HSP90AA1 (0.39) | HTR6DYRK1ARETKDRHSP90AA1 | |
| SCHEMBL26619531 | 0.68 | HSP90AA1 (0.35) | HTR6ATMDYRK1ARETHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235687-A1 | LRRK2 INHIBITORS | Brenig Therapeutics, Inc. (US) | 2025-11-13 | — | — | WO | disclosed |