SCHEMBL31726328

SCHEMBL31726328

Nc1cc(F)c(F)c(Cl)c1Br

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10619327 0.82 GAA (0.31) GAAALDH1A1
SCHEMBL28271960 0.78 GAA (0.35) GAAALDH1A1
SCHEMBL10616500 0.78 GAA (0.35) GAAALDH1A1
SCHEMBL1726754 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL3823002 0.77 KDM1A (0.32) GAAALDH1A1
SCHEMBL4706186 0.76 GAA (0.33) GAAALDH1A1
SCHEMBL10351195 0.74 GAA (0.32) GAAALDH1A1
SCHEMBL30395917 0.73 ALDH1A1 (0.33) GAAALDH1A1
SCHEMBL8525834 0.73 GAA (0.35) GAAALDH1A1
SCHEMBL31727384 0.73 CA1 (0.39) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235686-A1 FLUOROCAMPTOTHECIN COMPOUNDS, CONJUGATES, AND METHODS THEREOF Aarvik Therapeutics, Inc. (US) 2025-11-13 WO disclosed