Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395917 | 0.79 | ALDH1A1 (0.33) | ALDH1A1KDM1AKDM1BCA1CA2 | |
| SCHEMBL25292992 | 0.79 | POLB (0.34) | KDM1AKDM1BCA1CA2CA9 | |
| SCHEMBL31726328 | 0.78 | GAA (0.31) | ALDH1A1 | |
| SCHEMBL25027709 | 0.78 | AKR1B1 (0.33) | ALDH1A1CA1CA2 | |
| SCHEMBL1192817 | 0.77 | CA1 (0.33) | ALDH1A1KDM1AKDM1BCA1CA2 | |
| SCHEMBL25245756 | 0.75 | GAA (0.43) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL31258564 | 0.75 | CA1 (0.35) | KDM1AKDM1BCA1CA2CA12 | |
| SCHEMBL2933659 | 0.75 | CA1 (0.35) | KDM1AKDM1BCA1CA2CA12 | |
| SCHEMBL998262 | 0.75 | ALDH1A1 (0.38) | ALDH1A1LMNACA1CA2CA12 | |
| SCHEMBL31726708 | 0.73 | CA2 (0.38) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235686-A1 | FLUOROCAMPTOTHECIN COMPOUNDS, CONJUGATES, AND METHODS THEREOF | Aarvik Therapeutics, Inc. (US) | 2025-11-13 | — | — | WO | disclosed |
| US-12195473-B2 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2025-01-14 | — | — | US | disclosed |
| CN-115192577-B | KRAS mutein inhibitors | 北京加科思新药研发有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11787811-B2 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-10-17 | — | — | US | disclosed |
| US-20230011726-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2023-01-12 | — | — | US | disclosed |
| EP-4077326-A1 | KRAS MUTANT PROTEIN INHIBITORS | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| CN-115192577-A | KRAS mutein inhibitors | 北京加科思新药研发有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-11384087-B1 | — | — | 2022-07-12 | — | — | US | disclosed |
| US-20220213109-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2022-07-07 | — | — | US | disclosed |
| CN-113651814-B | KRAS mutein inhibitors | 北京加科思新药研发有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-10034476-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20170347650-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-9808006-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-07 | — | — | US | disclosed |
| US-20130317062-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-28 | — | — | US | disclosed |
| US-8518971-B2 | Insecticidal phenyl- or pyridyl-piperdine compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| WO-2012037282-A3 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2324010-B1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-11-30 | — | — | EP | disclosed |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-06-09 | — | — | US | disclosed |
| EP-2324010-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010009968-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230011726-A1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3978/4885LMNA 3922/4885KDM1A 3598/4885 |
| US-12195473-B2 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3978/4885LMNA 3922/4885KDM1A 3598/4885 |
| US-11384087-B1 | — | KRAS, NRAS, APC | ALDH1A1 3682/4885LMNA 4247/4885KDM1A 3076/4885 |
| US-10034476-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | ACHE, CHRM1, CHRM2 | ALDH1A1 253/4885LMNA 923/4885KDM1A 248/4885 |
| US-11787811-B2 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3978/4885LMNA 3922/4885KDM1A 3598/4885 |
| US-20130317062-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | ALDH1A1 253/4885LMNA 923/4885KDM1A 248/4885 |
| US-20220213109-A1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | ALDH1A1 3978/4885LMNA 3922/4885KDM1A 3598/4885 |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | ALDH1A1 261/4885LMNA 805/4885KDM1A 301/4885 |
| US-20170347650-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | ALDH1A1 253/4885LMNA 923/4885KDM1A 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.