Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727427 | 0.81 | TP53 (0.44) | ALDH1A1SMN1; SMN2MAPTPKMHTR6 | |
| SCHEMBL28852739 | 0.75 | MAPT (0.48) | LMNAALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL12616547 | 0.70 | SIGMAR1 (0.61) | LMNAALDH1A1MAPK1POLBSMN1; SMN2 | |
| SCHEMBL26879952 | 0.69 | ABCB1 (0.63) | — | |
| SCHEMBL23878154 | 0.69 | MAPT (0.61) | LMNAALDH1A1SMN1; SMN2MAPTPKM | |
| SCHEMBL31727476 | 0.68 | SIGMAR1 (0.54) | ALDH1A1POLBSMN1; SMN2MAPTPKM | |
| SCHEMBL28741860 | 0.68 | CA1 (0.56) | LMNAALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL10383284 | 0.68 | ABCB1 (0.74) | SMN1; SMN2MAPT | |
| SCHEMBL6868322 | 0.68 | RYR2 (0.60) | RYR2 | |
| SCHEMBL5870597 | 0.67 | ALDH1A1 (0.57) | LMNAALDH1A1SMN1; SMN2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235363-A1 | CYCLIN-DEPENDENT KINASE 4 DEGRADERS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-11-13 | — | — | WO | disclosed |