Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 16/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728062 | 0.85 | DGAT1 (0.33) | PTPN11DGAT1 | |
| SCHEMBL31728378 | 0.82 | IRAK4 (0.34) | KMOIRAK1IRAK4 | |
| SCHEMBL31728545 | 0.73 | DGAT1 (0.39) | PTPN11DGAT1 | |
| SCHEMBL31729221 | 0.70 | DGAT1 (0.41) | PTPN11DGAT1 | |
| SCHEMBL31728484 | 0.69 | PDE5A (0.46) | — | |
| SCHEMBL31728253 | 0.68 | PDE5A (0.42) | KMO | |
| SCHEMBL31728942 | 0.66 | MCL1 (0.33) | — | |
| SCHEMBL31727897 | 0.64 | LIMK1 (0.36) | — | |
| SCHEMBL31728863 | 0.63 | DGAT1 (0.39) | PTPN11DGAT1 | |
| SCHEMBL31727873 | 0.61 | SMN1; SMN2 (0.40) | PTPN11DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |