Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | DCK | P27707 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727770 | 0.82 | PTPN11 (0.39) | IRAK4IRAK1KMO | |
| SCHEMBL31728840 | 0.69 | ALOX5AP (0.39) | EGFRFEN1 | |
| SCHEMBL31728875 | 0.66 | SLC6A4 (0.38) | EGFRFEN1 | |
| SCHEMBL31728253 | 0.65 | PDE5A (0.42) | EGFRKMO | |
| SCHEMBL31728453 | 0.64 | CLK1 (0.38) | EGFRCLK1 | |
| SCHEMBL31728213 | 0.64 | EIF2AK3 (0.38) | EGFRCLK1 | |
| SCHEMBL31729157 | 0.64 | PDE5A (0.39) | EGFRERBB2CLK1 | |
| SCHEMBL31728332 | 0.63 | CLK1 (0.38) | CLK1 | |
| SCHEMBL31728545 | 0.62 | DGAT1 (0.39) | CLK1 | |
| SCHEMBL2775914 | 0.62 | MAP4K4 (0.44) | CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |