Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728796 | 0.85 | NR4A2 (0.37) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL31728402 | 0.78 | KMT2A (0.44) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL31727787 | 0.68 | IDO1 (0.36) | POLBLMNAALDH1A1IDO1KDM4E | |
| SCHEMBL31727767 | 0.67 | PARP1 (0.43) | ABL1IDO1 | |
| SCHEMBL34472491 | 0.67 | TDP1 (0.52) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL31728397 | 0.66 | IDO1 (0.34) | IDO1 | |
| SCHEMBL2211359 | 0.66 | KMT2A (0.50) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL30640280 | 0.65 | SLC6A4 (0.48) | MEN1KMT2ATDP1LMNAALDH1A1 | |
| SCHEMBL28489114 | 0.65 | SLC6A4 (0.48) | MEN1KMT2ATDP1LMNAALDH1A1 | |
| SCHEMBL31729329 | 0.65 | IDO1 (0.35) | MEN1KMT2AMAPTLMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |