Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.43 |
| ▸ | PIM1 | P11309 | 4/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727787 | 0.82 | IDO1 (0.36) | IDO1 | |
| SCHEMBL31728397 | 0.81 | IDO1 (0.34) | IDO1 | |
| SCHEMBL31729020 | 0.72 | KDM4C (0.47) | PARP1IDO1 | |
| SCHEMBL31728796 | 0.70 | NR4A2 (0.37) | ABL1IDO1 | |
| SCHEMBL31727784 | 0.67 | MEN1 (0.38) | ABL1IDO1 | |
| SCHEMBL31729250 | 0.64 | LRRK2 (0.40) | PIM1JAK2MAP4K4METJAK3 | |
| SCHEMBL31729329 | 0.63 | IDO1 (0.35) | IDO1 | |
| SCHEMBL21451423 | 0.63 | IDO1 (0.53) | LRRK2IDO1 | |
| SCHEMBL2447579 | 0.63 | PARP1 (1.00) | PARP1ACVR1PIM1AURKADAPK3 | |
| SCHEMBL28653289 | 0.60 | PARP1 (0.70) | PARP1ACVR1PIM1AURKADAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |