Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728796 | 0.73 | NR4A2 (0.37) | IDO1KMT2APDE4BMEN1LMNA | |
| SCHEMBL30593461 | 0.67 | KMT2A (0.51) | KMT2AHAVCR2MEN1USP2MT-CO2 | |
| SCHEMBL31728397 | 0.66 | IDO1 (0.34) | IDO1PDE4B | |
| SCHEMBL11760409 | 0.66 | KMT2A (0.44) | IDO1KMT2AHAVCR2CTSAMEN1 | |
| SCHEMBL31729020 | 0.65 | KDM4C (0.47) | IDO1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31727784 | 0.65 | MEN1 (0.38) | IDO1KMT2AMEN1LMNAMAPT | |
| SCHEMBL27965143 | 0.65 | KMT2A (0.51) | KMT2AMEN1USP2MT-CO2LMNA | |
| SCHEMBL21451423 | 0.64 | IDO1 (0.53) | IDO1KMT2AROCK2ROCK1 | |
| SCHEMBL27684556 | 0.64 | ALDH1A1 (0.44) | KMT2APDE4BARHPGDPTGS2 | |
| SCHEMBL31727767 | 0.63 | PARP1 (0.43) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |