Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.48 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 2/20 | 0.42 |
| ▸ | DHPS | P49366 | 2/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728478 | 0.81 | MAP4K4 (0.51) | CLK1MAP4K4LIMK1ADKIKBKE | |
| SCHEMBL31728910 | 0.79 | FYN (0.45) | CLK1MAP4K4FYNLIMK1ADK | |
| SCHEMBL31728470 | 0.79 | MAP4K4 (0.40) | CLK1MAP4K4LIMK1ADKIKBKE | |
| SCHEMBL31729265 | 0.77 | MAP4K4 (0.43) | CLK1MAP4K4FYNLIMK1ADK | |
| SCHEMBL31729150 | 0.75 | ADK (0.43) | CLK1MAP4K4FYNLIMK1ADK | |
| SCHEMBL31727817 | 0.75 | FYN (0.48) | CLK1MAP4K4FYNLIMK1DHPS | |
| SCHEMBL31728471 | 0.70 | MAP4K4 (0.53) | CLK1MAP4K4LIMK1DHFR | |
| SCHEMBL31728028 | 0.70 | MAP4K4 (0.50) | CLK1MAP4K4FYNLIMK1PDE5A | |
| SCHEMBL31727760 | 0.70 | MAP4K4 (0.48) | CLK1MAP4K4LIMK1ADKIKBKE | |
| SCHEMBL11446157 | 0.69 | MAP4K4 (0.61) | CLK1MAP4K4ADKDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |