Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.61 |
| ▸ | ADK | P55263 | 3/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478905 | 0.83 | PIK3CG (0.48) | MAP4K4PIK3CGADKCLK1ATR | |
| SCHEMBL11445170 | 0.83 | PIK3CG (0.61) | MAP4K4PIK3CGADKATR | |
| SCHEMBL11446163 | 0.82 | ADK (0.67) | PIK3CGADK | |
| SCHEMBL5321714 | 0.76 | ATR (0.55) | MAP4K4PIK3CGDHFRATR | |
| SCHEMBL15587270 | 0.76 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL3745255 | 0.76 | PIK3CG (1.00) | PIK3CGADK | |
| SCHEMBL22715806 | 0.75 | PIK3CG (0.61) | MAP4K4PIK3CGADK | |
| SCHEMBL29439870 | 0.75 | PIK3CG (0.61) | MAP4K4PIK3CGADK | |
| SCHEMBL5991130 | 0.75 | DHFR (0.53) | MAP4K4DHFRATR | |
| SCHEMBL3742485 | 0.74 | PIK3CG (0.72) | PIK3CGADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187307-A | 4-AMINOPTERIDINES | ABBOTT LABORATORIES (US) | 1980-02-05 | — | — | US | disclosed |