Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ABL2 | P42684 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | STK4 | Q13043 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727817 | 0.80 | FYN (0.48) | SRCABL1EGFRABL2KDR | |
| SCHEMBL31728532 | 0.79 | STK4 (0.52) | SRCABL1EGFRABL2KDR | |
| SCHEMBL31728046 | 0.77 | SRC (0.37) | SRCABL1EGFRABL2KDR | |
| SCHEMBL5581989 | 0.76 | DHFR (0.51) | MAP4K4FYNCLK1DHFRDHPS | |
| SCHEMBL31728028 | 0.75 | MAP4K4 (0.50) | SRCABL1EGFRABL2KDR | |
| SCHEMBL31728376 | 0.73 | MAP4K4 (0.53) | SRCABL1EGFRABL2KDR | |
| SCHEMBL31729137 | 0.73 | SRC (0.50) | SRCABL1EGFRABL2KDR | |
| SCHEMBL31728910 | 0.71 | FYN (0.45) | SRCABL1EGFRABL2KDR | |
| SCHEMBL5581717 | 0.71 | TSHR (0.39) | KDRFYNDHFRPDE5AMEN1 | |
| SCHEMBL5582085 | 0.70 | CSNK2A2 (0.38) | EGFRMAP4K4FYNDHFRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |