Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582020 | 0.89 | ADORA1 (0.40) | CSNK2A2CSNK2BCSNK2A1KMT2AADORA1 | |
| SCHEMBL5581933 | 0.89 | CCR4 (0.33) | CSNK2A2CSNK2BCSNK2A1ADORA1EGFR | |
| SCHEMBL5581817 | 0.89 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1MEN1TSHR | |
| SCHEMBL5582009 | 0.89 | ADORA1 (0.41) | CSNK2A2CSNK2BCSNK2A1MEN1TSHR | |
| SCHEMBL5581980 | 0.88 | NQO2 (0.36) | CSNK2A2CSNK2BMEN1KMT2AJAK2 | |
| SCHEMBL5581986 | 0.88 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1ADORA1MAP4K4 | |
| SCHEMBL5582141 | 0.88 | NQO2 (0.41) | CSNK2A1ADORA1EGFRNQO2 | |
| SCHEMBL5581820 | 0.87 | ADORA1 (0.43) | CSNK2A2CSNK2BCSNK2A1ADORA1MAP4K4 | |
| SCHEMBL5581776 | 0.87 | FYN (0.39) | ADORA1MAP4K4SCN9AEGFRFYN | |
| SCHEMBL5581799 | 0.87 | FYN (0.41) | CSNK2A2CSNK2BCSNK2A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225308-A1 | 2-Amino Quinazoline Derivative | KYOWA HAKKO KOGYO CO.,LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1726584-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225308-A1 | 2-Amino Quinazoline Derivative | AGTR2, ABL1, AGTR1 | CSNK2A2 467/4885CSNK2B 662/4885CSNK2A1 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.