Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 17/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728518 | 0.93 | GRM5 (0.37) | PTPN11GRM5GRM4SSTR5 | |
| SCHEMBL31729003 | 0.78 | GRM5 (0.36) | GRM5SSTR5 | |
| SCHEMBL31728909 | 0.64 | PTPN11 (0.32) | PTPN11 | |
| SCHEMBL31728797 | 0.62 | KDM4E (0.43) | PTPN11 | |
| SCHEMBL31728947 | 0.59 | TARBP2 (0.40) | — | |
| SCHEMBL6167288 | 0.54 | TDP1 (0.44) | — | |
| SCHEMBL12235127 | 0.54 | GRM5 (0.70) | GRM5GRM4 | |
| SCHEMBL26762244 | 0.54 | GRM2 (0.32) | — | |
| SCHEMBL5802725 | 0.53 | DGAT1 (0.46) | — | |
| SCHEMBL16075495 | 0.52 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |