Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 5/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727944 | 0.90 | KHK (0.38) | KHKGRM4SIGMAR1EGLN2EGFR | |
| SCHEMBL31728421 | 0.84 | — | — | |
| SCHEMBL31727929 | 0.82 | KHK (0.37) | KHKEGLN2EGFR | |
| SCHEMBL31729227 | 0.82 | IP6K1 (0.32) | CNR1 | |
| SCHEMBL31728559 | 0.74 | CLK1 (0.33) | — | |
| SCHEMBL31728772 | 0.72 | KHK (0.39) | KHKEGLN2CNR1CNR2EGFR | |
| SCHEMBL31729173 | 0.72 | CLK1 (0.35) | EGFR | |
| SCHEMBL31728352 | 0.72 | PIK3CD (0.34) | KHKEGFR | |
| SCHEMBL31728591 | 0.66 | EIF2AK3 (0.39) | EGFR | |
| SCHEMBL31728018 | 0.64 | CLK1 (0.36) | CYP1A2CYP2C9CYP2C19NPSR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |