Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728912 | 0.85 | NSD2 (0.35) | PIK3CDPIK3CAPIK3CBPIK3CGEPHB4 | |
| SCHEMBL31728436 | 0.84 | PIK3CD (0.37) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31727822 | 0.82 | EIF2AK3 (0.31) | EIF2AK3 | |
| SCHEMBL31728546 | 0.82 | — | — | |
| SCHEMBL31728414 | 0.82 | — | — | |
| SCHEMBL31727929 | 0.82 | KHK (0.37) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31727944 | 0.80 | KHK (0.38) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31728886 | 0.76 | KDR (0.34) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31728772 | 0.75 | KHK (0.39) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31728549 | 0.74 | MET (0.33) | PIK3CDABL1EGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |