Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729228 | 0.80 | LRRK2 (0.39) | PIK3CAPIK3CDPIK3CBLRRK2MEN1 | |
| SCHEMBL31728797 | 0.67 | KDM4E (0.43) | PIK3CAMEN1KMT2A | |
| SCHEMBL28496580 | 0.67 | PIK3CD (0.54) | PIK3CAPIK3CDPIK3CBLRRK2MAPK14 | |
| SCHEMBL31727987 | 0.64 | L3MBTL1 (0.43) | MEN1KMT2A | |
| SCHEMBL31728909 | 0.63 | PTPN11 (0.32) | AKT1 | |
| SCHEMBL31728230 | 0.61 | KMT2A (0.35) | SRCLRRK2MAPK14KMT2A | |
| SCHEMBL18123516 | 0.60 | CHEK1 (0.37) | SRCLRRK2 | |
| SCHEMBL30540190 | 0.60 | TSHR (0.51) | MEN1KMT2A | |
| SCHEMBL26635221 | 0.60 | TSHR (0.51) | MEN1KMT2A | |
| SCHEMBL13257521 | 0.59 | PIK3CA (0.75) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |