Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.35 |
| ▸ | STK3 | Q13188 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728909 | 0.82 | PTPN11 (0.32) | ALDH1A1HSD17B10 | |
| SCHEMBL31728150 | 0.80 | SRC (0.38) | LRRK2PIK3CAPIK3CDPIK3CBMEN1 | |
| SCHEMBL31728069 | 0.71 | CLK1 (0.39) | — | |
| SCHEMBL31728797 | 0.70 | KDM4E (0.43) | PIK3CAKDM4EGAAPIK3R1MTOR | |
| SCHEMBL31728617 | 0.69 | PIK3CD (0.49) | PIK3CAPIK3CDPIK3CBMTOR | |
| SCHEMBL31728431 | 0.67 | MAP4K4 (0.34) | — | |
| SCHEMBL31729167 | 0.67 | MAP4K4 (0.34) | — | |
| SCHEMBL10659846 | 0.66 | KDM4E (0.49) | PIK3CAPIK3CDPIK3CBADKKDM4E | |
| SCHEMBL10657255 | 0.66 | KDM4E (0.55) | LRRK2PIK3CAPIK3CDPIK3CBADK | |
| SCHEMBL31729163 | 0.64 | CLK1 (0.37) | PIK3CAPIK3CDPIK3CBMTORSTK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |