Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 12/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728860 | 0.84 | ALOX5AP (0.37) | GRM2EIF2AK3MPOCYP3A4ALOX5AP | |
| SCHEMBL31727769 | 0.83 | GRM2 (0.36) | GRM2MPOCYP3A4ALOX5APFEN1 | |
| SCHEMBL31727952 | 0.81 | EIF2AK3 (0.42) | EIF2AK3PIK3CBPIK3CGPRKDC | |
| SCHEMBL31729288 | 0.79 | EIF2AK3 (0.35) | EIF2AK3KCNH2 | |
| SCHEMBL31728395 | 0.78 | PDCD1 (0.35) | GRM2MPOCYP3A4ALOX5APFEN1 | |
| SCHEMBL31728454 | 0.78 | EIF2AK3 (0.36) | EIF2AK3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL31728922 | 0.71 | PIK3CD (0.33) | EIF2AK3MPOPIK3CDPIK3CAPIK3CB | |
| SCHEMBL31728520 | 0.70 | EGFR (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL31729134 | 0.69 | GSK3B (0.41) | EIF2AK3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL31728528 | 0.68 | IDO1 (0.36) | ALOX5APFEN1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |