Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 11/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728454 | 0.83 | EIF2AK3 (0.36) | EIF2AK3EPHB4DPP4PTPN11 | |
| SCHEMBL31728178 | 0.79 | GRM2 (0.37) | EIF2AK3KCNH2 | |
| SCHEMBL31727951 | 0.73 | DPP4 (0.33) | EPHB4DPP4PTPN11 | |
| SCHEMBL31728959 | 0.73 | EPHB4 (0.36) | EIF2AK3EPHB4DPP4PTPN11 | |
| SCHEMBL31728235 | 0.71 | SCN9A (0.35) | EIF2AK3DPP4PTPN11 | |
| SCHEMBL31727952 | 0.71 | EIF2AK3 (0.42) | EIF2AK3EPHB4 | |
| SCHEMBL31728468 | 0.71 | ERBB2 (0.37) | EPHB4 | |
| SCHEMBL31729317 | 0.66 | EGFR (0.41) | EPHB4 | |
| SCHEMBL31728545 | 0.65 | DGAT1 (0.39) | PTPN11 | |
| SCHEMBL31729157 | 0.65 | PDE5A (0.39) | EIF2AK3EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |