Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 12/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727951 | 0.90 | DPP4 (0.33) | DPP4PTPN11EPHB4EGFRPIK3CD | |
| SCHEMBL31728959 | 0.89 | EPHB4 (0.36) | EIF2AK3DPP4PTPN11EPHB4EGFR | |
| SCHEMBL31728235 | 0.87 | SCN9A (0.35) | EIF2AK3DPP4PTPN11 | |
| SCHEMBL31728468 | 0.87 | ERBB2 (0.37) | EPHB4EGFRERBB2PIK3CDPIK3CA | |
| SCHEMBL31729288 | 0.83 | EIF2AK3 (0.35) | EIF2AK3DPP4PTPN11EPHB4 | |
| SCHEMBL31728589 | 0.82 | SCN9A (0.32) | — | |
| SCHEMBL31727830 | 0.81 | HTR2C (0.36) | EIF2AK3PTPN11EPHB4EGFRPIK3CD | |
| SCHEMBL31728353 | 0.81 | HTR2C (0.36) | EIF2AK3PTPN11EPHB4EGFRPIK3CD | |
| SCHEMBL31728886 | 0.79 | KDR (0.34) | EIF2AK3EPHB4EGFRERBB2PIK3CD | |
| SCHEMBL31728178 | 0.78 | GRM2 (0.37) | EIF2AK3PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |