Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729263 | 1.00 | MAPK1 (0.39) | MAPK1L3MBTL1MAPTKMT2ANPC1 | |
| SCHEMBL31727772 | 0.79 | L3MBTL1 (0.39) | MAPK1L3MBTL1MAPTKMT2ANPC1 | |
| SCHEMBL31727964 | 0.79 | L3MBTL1 (0.39) | MAPK1L3MBTL1MAPTKMT2ANPC1 | |
| SCHEMBL28808821 | 0.77 | ALDH1A1 (0.36) | L3MBTL1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31368737 | 0.77 | KDM4E (0.36) | MAPK1L3MBTL1MAPTKMT2ARAB9A | |
| SCHEMBL29149630 | 0.76 | — | — | |
| SCHEMBL31368749 | 0.76 | ALDH1A1 (0.36) | MAPK1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23751843 | 0.75 | GAA (0.35) | MAPK1L3MBTL1MAPTKMT2AKDM4E | |
| SCHEMBL4374319 | 0.74 | PDGFRB (0.35) | L3MBTL1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24386895 | 0.74 | ALDH1A1 (0.34) | L3MBTL1MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |