SCHEMBL31728221

SCHEMBL31728221

CN(Cc1nn(C)c2cccc(Cl)c12)C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HTR2C P28335 5/20 0.41
▸ SLC6A4 P31645 5/20 0.41
▸ CCR4 P51679 2/20 0.38
▸ LMNA P02545 3/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ SLC16A3 O15427 4/20 0.35
▸ SLC16A1 P53985 4/20 0.35
▸ MAPK14 Q16539 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ USP2 O75604 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ MCTS1 Q9ULC4 1/20 0.34
▸ CCNE2 O96020 1/20 0.34
▸ CCNE1 P24864 1/20 0.34
▸ CDK2 P24941 1/20 0.34
▸ HPGD P15428 1/20 0.33
▸ GLS O94925 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31728953 0.78 POLB (0.49) CCR4LMNAGAATSHRHPGD
SCHEMBL29383049 0.69 HTR2C (0.37) HTR2CSLC6A4LMNA
SCHEMBL25573068 0.69 HTR2C (0.41) HTR2CSLC6A4GLS
SCHEMBL23953613 0.68 HTR2C (0.40) HTR2CSLC6A4LMNAGAAALDH1A1
SCHEMBL15273657 0.68 HTR2C (0.36) HTR2CSLC6A4
SCHEMBL15273661 0.68 HTR2C (0.38) HTR2CSLC6A4GLS
SCHEMBL29865899 0.67 SSTR4 (0.40) HTR2CSLC6A4GLS
SCHEMBL29385268 0.67 HTR2C (0.39) HTR2CSLC6A4NPC1
SCHEMBL15274027 0.67 KDM4E (0.43) HTR2CSLC6A4LMNAMAPTMAPK14
SCHEMBL7522351 0.67 ALDH1A1 (0.58) LMNANPC1MAPTALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025236004-A1 STAT6 INHIBITORS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2025-11-13 — — WO disclosed
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