Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | CCR4 | P51679 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728221 | 0.78 | HTR2C (0.41) | CCR4LMNAGAAHPGDTSHR | |
| SCHEMBL31729055 | 0.76 | CCR4 (0.38) | CCR4GAA | |
| SCHEMBL21484075 | 0.75 | POLB (0.59) | POLBMAPK1ATMDRD2LMNA | |
| SCHEMBL19782521 | 0.74 | POLB (0.45) | POLBMAPK1ATMDRD2LMNA | |
| SCHEMBL27002206 | 0.73 | PARP1 (0.54) | POLBMAPK1ATMDRD2PRMT5 | |
| SCHEMBL14907839 | 0.71 | POLB (0.53) | POLBMAPK1ATMDRD2LMNA | |
| SCHEMBL26616825 | 0.71 | NPSR1 (0.49) | POLBMAPK1ATMLMNAGAA | |
| SCHEMBL29076147 | 0.70 | POLB (0.52) | POLBMAPK1ATMDRD2LMNA | |
| SCHEMBL26147436 | 0.70 | NPC1 (0.60) | POLBMAPK1ATMLMNAHPGD | |
| SCHEMBL12680199 | 0.70 | POLB (0.48) | POLBMAPK1ATMLMNAKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025236004-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |