Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HCK | P08631 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728933 | 0.85 | PIK3CD (0.31) | ABL1EGFRHCKSRCKDR | |
| SCHEMBL31728487 | 0.85 | MET (0.31) | METABL1EGFRHCKSRC | |
| SCHEMBL31728491 | 0.85 | MET (0.38) | METABL1EGFRHCKSRC | |
| SCHEMBL31728408 | 0.84 | PIK3CD (0.30) | ABL1EGFRHCKSRCKDR | |
| SCHEMBL31727755 | 0.80 | SRC (0.34) | ABL1EGFRHCKSRCKDR | |
| SCHEMBL31728370 | 0.79 | SRC (0.30) | SRC | |
| SCHEMBL31729300 | 0.79 | MET (0.35) | METALKABL1EGFRHCK | |
| SCHEMBL31728810 | 0.78 | TSHR (0.42) | METSRCHTR2A | |
| SCHEMBL31728587 | 0.78 | SRC (0.31) | ABL1EGFRHCKSRCKDR | |
| SCHEMBL31728213 | 0.77 | EIF2AK3 (0.38) | ABL1EGFRHCKSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |