SCHEMBL31728491 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	MET	P08581	6/20	0.38

▸	PIK3CD	O00329	2/20	0.35

▸	ABL1	P00519	2/20	0.35

▸	EGFR	P00533	2/20	0.35

▸	HCK	P08631	2/20	0.35

▸	SRC	P12931	2/20	0.35

▸	KDR	P35968	2/20	0.35

▸	PIK3CA	P42336	2/20	0.35

▸	PIK3CB	P42338	2/20	0.35

▸	MTOR	P42345	2/20	0.35

▸	PIK3CG	P48736	2/20	0.35

▸	EPHB4	P54760	2/20	0.35

▸	PRKDC	P78527	2/20	0.35

▸	EIF2AK3	Q9NZJ5	1/20	0.31

▸	LRRK2	Q5S007	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31728487	0.86	MET (0.31)	METPIK3CDABL1EGFRHCK
SCHEMBL31728243	0.85	MET (0.34)	METPIK3CDABL1EGFRHCK
SCHEMBL31729300	0.81	MET (0.35)	METPIK3CDABL1EGFRHCK
SCHEMBL31728941	0.80	EIF2AK3 (0.39)	METPIK3CDABL1EGFRHCK
SCHEMBL31728995	0.80	ABL1 (0.30)	PIK3CDABL1EGFRHCKSRC
SCHEMBL31729192	0.79	PIK3CD (0.34)	METPIK3CDABL1EGFRHCK
SCHEMBL31728758	0.79	PIK3CD (0.34)	METPIK3CDABL1EGFRHCK
SCHEMBL31728112	0.79	MET (0.33)	METPIK3CDABL1EGFRHCK
SCHEMBL31727950	0.79	MET (0.33)	METPIK3CDABL1EGFRHCK
SCHEMBL31727909	0.78	MET (0.33)	METPIK3CDABL1EGFRHCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025235874-A1	HETEROCYCLICS AS EGFR INHIBITORS	SCHRÖDINGER, INC. (US)	2025-11-13	—	—	WO	disclosed