Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728402 | 0.81 | KMT2A (0.44) | SLC6A3NR4A2KDM4EMEN1KMT2A | |
| SCHEMBL24792656 | 0.76 | GAA (0.49) | ABL1GAAKDM4EALDH1A1MAPT | |
| SCHEMBL31728796 | 0.76 | NR4A2 (0.37) | ABL1NR4A2GAAMEN1KMT2A | |
| SCHEMBL15975999 | 0.76 | SLC6A3 (0.52) | SLC6A3GAASLC6A4KDM4EMEN1 | |
| SCHEMBL31160526 | 0.73 | GAA (0.44) | SLC6A3ABL1NR4A2GAAMEN1 | |
| SCHEMBL23089980 | 0.73 | GAA (0.44) | SLC6A3ABL1NR4A2GAAMEN1 | |
| SCHEMBL759268 | 0.72 | KDM4E (0.47) | ABL1NR4A2GAAKDM4EALDH1A1 | |
| SCHEMBL724484 | 0.71 | NR4A2 (0.53) | SLC6A3NR4A2SLC6A4KDM4EMEN1 | |
| SCHEMBL30593461 | 0.71 | KMT2A (0.51) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18164140 | 0.71 | GAA (0.50) | ABL1GAAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |