Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 7/20 | 0.39 |
| ▸ | MET | P08581 | 11/20 | 0.36 |
| ▸ | EIF2AK3 | Q9NZJ5 | 4/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729172 | 0.81 | MET (0.37) | ALKMET | |
| SCHEMBL31728379 | 0.78 | JAK2 (0.36) | ALKMET | |
| SCHEMBL31728736 | 0.78 | JAK2 (0.36) | ALKMET | |
| SCHEMBL31728810 | 0.78 | TSHR (0.42) | METEIF2AK3 | |
| SCHEMBL31728243 | 0.76 | MET (0.34) | ALKMET | |
| SCHEMBL31727766 | 0.75 | ESR1 (0.36) | METEIF2AK3 | |
| SCHEMBL31728213 | 0.75 | EIF2AK3 (0.38) | EIF2AK3 | |
| SCHEMBL31728923 | 0.71 | POLB (0.36) | ALKMET | |
| SCHEMBL31729163 | 0.67 | CLK1 (0.37) | ROS1AXL | |
| SCHEMBL31727792 | 0.67 | PDCD1LG2 (0.36) | ALKEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |