Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728623 | 0.76 | SMN1; SMN2 (0.39) | MAP4K4ALDH1A1SMN1; SMN2RET | |
| SCHEMBL31729236 | 0.69 | HTR2C (0.43) | MAP4K4HPGDBTKNPC1RAB9A | |
| SCHEMBL31729250 | 0.69 | LRRK2 (0.40) | MAP4K4 | |
| SCHEMBL31727998 | 0.67 | MAP4K4 (0.49) | MAP4K4 | |
| SCHEMBL29828939 | 0.67 | MAP4K4 (0.51) | MAP4K4HPGDMAPTSMN1; SMN2 | |
| SCHEMBL31727897 | 0.66 | LIMK1 (0.36) | MAP4K4HPGDALDH1A1MAPTNPC1 | |
| SCHEMBL29829109 | 0.66 | MAP4K4 (0.50) | MAP4K4HPGDMAPTSMN1; SMN2GLA | |
| SCHEMBL31729240 | 0.65 | PIK3CD (0.37) | ALDH1A1 | |
| SCHEMBL31727873 | 0.63 | SMN1; SMN2 (0.40) | MAP4K4SMN1; SMN2 | |
| SCHEMBL31728766 | 0.63 | PIK3CD (0.38) | ALDH1A1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |