Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728000 | 0.73 | NUDT1 (0.43) | PTPN11LMNADGAT1 | |
| SCHEMBL31728859 | 0.69 | MAP4K4 (0.41) | BTKNPC1GLAHPGDRAB9A | |
| SCHEMBL29828939 | 0.68 | MAP4K4 (0.51) | GAAHPGDLMNAHTTMAP4K4 | |
| SCHEMBL29829109 | 0.67 | MAP4K4 (0.50) | GAAGLAHPGDLMNAXBP1 | |
| SCHEMBL31729240 | 0.66 | PIK3CD (0.37) | CNR2ABL1HTT | |
| SCHEMBL31727998 | 0.66 | MAP4K4 (0.49) | CNR2CNR1PTPN11DGAT1MAP4K4 | |
| SCHEMBL29944015 | 0.65 | HPGD (0.67) | HTR2CGAAKMT2ANPC1GLA | |
| SCHEMBL31728885 | 0.65 | CNR2 (0.40) | CNR2CNR1PTPN11ABL1DGAT1 | |
| SCHEMBL31728417 | 0.64 | NUDT1 (0.37) | PTPN11MAP4K4 | |
| SCHEMBL4980893 | 0.64 | P2RX7 (0.72) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |