Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728397 | 0.83 | IDO1 (0.34) | IDO1 | |
| SCHEMBL31728623 | 0.77 | SMN1; SMN2 (0.39) | IDO1TGFBR1MAP4K4 | |
| SCHEMBL21451423 | 0.73 | IDO1 (0.53) | LRRK2IDO1ROCK2ROCK1 | |
| SCHEMBL31727787 | 0.72 | IDO1 (0.36) | IDO1 | |
| SCHEMBL31727938 | 0.70 | PRKCZ (0.39) | ROCK2ROCK1 | |
| SCHEMBL31728859 | 0.69 | MAP4K4 (0.41) | MAP4K4 | |
| SCHEMBL31728730 | 0.68 | PDE5A (0.36) | IDO1TGFBR1MAP4K4 | |
| SCHEMBL31728766 | 0.67 | PIK3CD (0.38) | IDO1 | |
| SCHEMBL31727895 | 0.66 | PIK3CD (0.38) | LRRK2IDO1JAK2JAK3MAP4K4 | |
| SCHEMBL13874691 | 0.66 | MAP4K4 (0.60) | MAP4K4PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |