Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728160 | 0.78 | ALDH1A1 (0.38) | KDM4EEGFR | |
| SCHEMBL31729179 | 0.78 | MAP4K4 (0.41) | KDM4E | |
| SCHEMBL31373275 | 0.74 | KDM4E (0.44) | KDM4EMPIL3MBTL1 | |
| SCHEMBL22221946 | 0.73 | PARP1 (0.44) | KDM4EMPIL3MBTL1 | |
| SCHEMBL24399770 | 0.70 | NQO2 (0.31) | KDM4EMPIL3MBTL1 | |
| SCHEMBL2158991 | 0.69 | KDM4E (0.42) | KDM4EMPIL3MBTL1EGFR | |
| SCHEMBL3219288 | 0.68 | KDM4E (0.33) | KDM4EMPIL3MBTL1 | |
| SCHEMBL31373294 | 0.67 | KDM4E (0.38) | KDM4EL3MBTL1 | |
| SCHEMBL18133910 | 0.67 | EGFR (0.32) | EGFR | |
| SCHEMBL26967299 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |