Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | ABL2 | P42684 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729246 | 0.85 | DGAT1 (0.39) | CNR2DGAT1 | |
| SCHEMBL31729200 | 0.82 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL31728602 | 0.72 | CNR2 (0.49) | CNR2MAP4K4DGAT1 | |
| SCHEMBL18291721 | 0.69 | ALOX5AP (0.40) | MTORUSP30EGLN2 | |
| SCHEMBL31728568 | 0.68 | DGAT1 (0.41) | CNR2MAP4K4DGAT1 | |
| SCHEMBL31727998 | 0.68 | MAP4K4 (0.49) | CNR1CNR2MAP4K4DGAT1 | |
| SCHEMBL31729125 | 0.67 | DGAT1 (0.38) | DGAT1SCN9A | |
| SCHEMBL31728456 | 0.67 | GRM5 (0.38) | CNR2DGAT1 | |
| SCHEMBL30125742 | 0.67 | EGFR (0.48) | EGFR | |
| SCHEMBL28829167 | 0.66 | ROCK2 (0.48) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |