SCHEMBL31729324

SCHEMBL31729324

COc1cccnc1-c1nc(N)sc1C(=O)Nc1c(C)cccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 16/20 0.49
LCK P06239 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539962 0.78 LCK (0.66) CHRNA7LCK
SCHEMBL1540351 0.77 CHRNA7 (0.60) CHRNA7LCK
SCHEMBL1539906 0.76 LCK (0.60) CHRNA7LCK
SCHEMBL6432872 0.72 CHRNA7 (0.54) CHRNA7LCK
SCHEMBL6432875 0.71 CHRNA7 (0.53) CHRNA7LCK
SCHEMBL12982110 0.70 CHRNA7 (0.63) CHRNA7LCK
SCHEMBL4701016 0.69 PDE4A (0.73) CHRNA7
SCHEMBL1540033 0.69 LCK (0.74) CHRNA7LCK
SCHEMBL29616014 0.69 MAPK14 (0.67) LCK
SCHEMBL1540030 0.69 MAPK14 (0.67) LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025231563-A1 SUBSTITUTED TRICYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS UNIVERSITE DE MONTREAL (CA) 2025-11-13 WO disclosed