Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729420 | 0.88 | GPR119 (0.36) | FPR2GPR119IDO1TDO2PIK3R1 | |
| SCHEMBL31729435 | 0.87 | FPR2 (0.41) | FPR2GPR119IDO1TDO2PIK3R1 | |
| SCHEMBL31728771 | 0.87 | FPR2 (0.41) | FPR2GPR119IDO1TDO2PIK3R1 | |
| SCHEMBL23102325 | 0.77 | GPR119 (0.39) | FPR2GPR119IDO1TDO2PIK3R1 | |
| SCHEMBL23102319 | 0.77 | GPR119 (0.39) | FPR2GPR119IDO1TDO2PIK3R1 | |
| SCHEMBL24763756 | 0.77 | TIPARP (0.41) | GPR119PIK3R1PIK3CA | |
| SCHEMBL31022119 | 0.77 | TIPARP (0.41) | GPR119PIK3R1PIK3CA | |
| SCHEMBL17068158 | 0.76 | USP30 (0.43) | FPR2GPR119SCN9ATP53 | |
| SCHEMBL31727586 | 0.76 | GPR119 (0.47) | GPR119SMARCA2SMARCA4PBRM1TP53 | |
| SCHEMBL24763869 | 0.75 | GPR119 (0.40) | GPR119IDO1TDO2SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231563-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |