SCHEMBL31730317

SCHEMBL31730317

COc1ccc2c(c1C#N)Nc1ccccc1S2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 8/20 0.48
GAA P10253 5/20 0.44
MAPT P10636 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 2/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SNCA P37840 3/20 0.43
BCHE P06276 2/20 0.43
ACHE P22303 2/20 0.43
ALOX15 P16050 2/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105775 0.77 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL29242179 0.76 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL4626664 0.75 NOX1 (0.48) NOX1GAAMAPTMEN1KMT2A
SCHEMBL1853045 0.74 NOX1 (0.47) NOX1GAAMAPTMEN1KMT2A
SCHEMBL5411776 0.74 ALOX5 (0.57) NOX1GAAMAPTMEN1KMT2A
SCHEMBL2583563 0.71 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL6545376 0.70 GAA (0.44) NOX1GAAMAPTMEN1KMT2A
SCHEMBL15909030 0.70 NOX1 (0.44) NOX1GAAMAPTMEN1KMT2A
SCHEMBL10501198 0.70 NOX1 (0.51) NOX1GAAMAPTMEN1KMT2A
SCHEMBL6206910 0.69 MAPT (0.43) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12502661-B2 Catalysts for synthesizing cyclic carbonates, preparation methods and uses thereof ANHUI CONCH MATERIAL TECHNOLOGY CO., LTD. (CN) 2025-12-23 US disclosed
US-20250352989-A1 CATALYSTS FOR SYNTHESIZING CYCLIC CARBONATES, PREPARATION METHODS AND USES THEREOF ANHUI CONCH MATERIAL TECH CO LTD (CN) 2025-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250352989-A1 CATALYSTS FOR SYNTHESIZING CYCLIC CARBONATES, PREPARATION METHODS AND USES THEREOF PBRM1, POLL, PPOX NOX1 2100/4885GAA 648/4885MAPT 928/4885
US-12502661-B2 Catalysts for synthesizing cyclic carbonates, preparation methods and uses thereof PBRM1, POLL, PPOX NOX1 2100/4885GAA 648/4885MAPT 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.