Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577396 | 0.88 | DGAT1 (0.35) | KMT2AMEN1DGAT1ALDH1A1LMNA | |
| SCHEMBL31730690 | 0.87 | DGAT1 (0.35) | KMT2AMEN1DGAT1ALDH1A1LMNA | |
| SCHEMBL16427447 | 0.85 | DGAT1 (0.37) | KMT2AMEN1DGAT1PKMNPC1 | |
| SCHEMBL31381599 | 0.85 | DGAT1 (0.37) | KMT2AMEN1DGAT1PKMNPC1 | |
| SCHEMBL31730412 | 0.84 | DGAT1 (0.34) | KMT2AMEN1DGAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31730788 | 0.84 | DGAT1 (0.34) | KMT2AMEN1DGAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21904215 | 0.81 | CALCRL (0.34) | DGAT1PKMANPEPHDAC3HDAC1 | |
| SCHEMBL2541904 | 0.79 | PKM (0.41) | KMT2AMEN1DGAT1ALDH1A1LMNA | |
| SCHEMBL16412685 | 0.78 | DGAT1 (0.34) | DGAT1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16277931 | 0.78 | PKM (0.38) | KMT2AMEN1DGAT1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353817-A1 | INTERLUKIN-17A INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353817-A1 | INTERLUKIN-17A INHIBITORS AND USES THEREOF | IL17A, IL15, IL23R | KMT2A 3804/4885MEN1 2643/4885DGAT1 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.