Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.50 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231775 | 0.93 | IKZF2 (0.59) | CRBNDDB1IKZF2GSPT1ALDH1A1 | |
| SCHEMBL21760140 | 0.85 | IKZF2 (0.59) | CRBNDDB1IKZF2GSPT1CSNK1A1 | |
| SCHEMBL27376752 | 0.85 | CRBN (0.56) | CRBNDDB1GSPT1 | |
| SCHEMBL21069262 | 0.85 | CRBN (0.63) | CRBNDDB1IKZF2GSPT1ALDH1A1 | |
| SCHEMBL27223126 | 0.85 | CRBN (0.56) | CRBNDDB1IKZF2 | |
| SCHEMBL20046720 | 0.85 | CRBN (0.56) | CRBNDDB1GSPT1 | |
| SCHEMBL29614584 | 0.85 | CRBN (0.56) | CRBNDDB1GSPT1 | |
| SCHEMBL27376693 | 0.85 | CRBN (0.56) | CRBNDDB1IKZF2 | |
| SCHEMBL30005464 | 0.82 | CRBN (0.57) | CRBNDDB1IKZF2GSPT1CSNK1A1 | |
| SCHEMBL27090509 | 0.82 | CRBN (0.57) | CRBNDDB1IKZF2GSPT1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606533-B2 | 3-phenylpropylamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2026-04-21 | — | — | US | disclosed |
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | SF1, SF3A1, SFXN1 | CRBN 2290/4885DDB1 1201/4885IKZF2 3767/4885 |
| US-12606533-B2 | 3-phenylpropylamine derivative | SF3A1, SF1, HTR1D | CRBN 2904/4885DDB1 363/4885IKZF2 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.